Mel Silverman is currently Senior Staff Nephrologist at the Toronto General Hospital, University Health Network, University of Toronto Professor Emeritus of Medicine, and Vice President – Research at the Canadian Institute for Advanced Research. He has published more than 100 original scientific research papers concerning the molecular physiology of Na+/glucose co-transporter, extracellular matrix – cell signaling in the glomerulus, and the role of RabGTPase 34 and its effector- hmunc 13 in the regulation of the plasminogen/plasmin system and apoptosis. He has played a national leadership role in Clinician Scientist Training, serving at the University of Toronto as Director of the MD/PhD Program (since 1984), Director of the Royal College Clinical Investigator Program (CIP) (since 1995), and Director of the Institute of Medical Science (1991-2000). He is currently Chair of the Royal College CIP advisory committee (since Dec. 2000).