Manuel Buchwald served as the Chief of Research at The Hospital for Sick Children, one of the premier research hospitals in the world, where he introduced a new matrix structure to bring together scientists from disparate disciplines and professions. He is one of the co-discoverers of the Cystic Fibrosis gene, a milestone in human genetics research. Dr. Buchwald also transformed research in Fanconi anemia by defining its genetic heterogeneity and cloning the first gene. Dr. Buchwald is an Officer of the Order of Canada and a Fellow of the Royal Society of Canada.