Dr. Marliss is an exemplary, widely-collaborative MD clinician-scientist in the areas of obesity and diabetes. His group is internationally recognized for showing that abnormal protein metabolism in these diseases accompanies that of glucose, and how to correct it. An amino acid "metabolomic signature" in these states predicts diabetes risk. Brain research during a weight reduction diet identified signals associated with success. A rat type 1 diabetes syndrome he discovered gave insights into the human disease. He has been a dedicated physician, nutrition teacher, committee member, and exceptional mentor to many trainees and junior faculty, most of whom became successful academics.