Dr Manns is a Specialist in Kidney Diseases, the Svare Professor in Health Economics and the Associate Chief Medical Officer of Alberta Health Service's Strategic Clinical Networks. His unique research expertise in applied health economics, health care policy and pragmatic trials has led him to contribute to significant policy changes in cancer screening, drug policy and patient-oriented kidney care. His 372 publications (95 with his research trainees) have been cited 38860 times (H-index 82). He has received over $50 million as the Principal Investigator including a CIHR Foundation grant (2016-2023). He has given 70 invited addresses nationally and internationally.