His major contributions are in prevention and control of hypertension, specifically in the knowledge translation of optimal treatment. He was the first Chair of the Canadian Hypertension Education Program. As well, he served as the founding President of Hypertension Canada, now the second largest cardiovascular disease not-for-profit agency in Canada. He is the author of more than 200 original manuscripts, reviews and book chapters. His clinical research focuses on development of innovative strategies to improve blood pressure control. His fundamental research focuses on elucidation of novel cell signaling mechanisms of vascular regulation/dysregulation linked to the development of hypertension and atherosclerosis.