Dr. John Yeow is widely recognized for his pioneering contributions to the fields of microsystems and nanodevices research, particularly as they apply to medical and therapeutic instruments. His work has had a broad and seminal impact - from discovery to industrial innovation. He was the first to develop a 3-dimensional (3D) micromachine-based optical coherent tomographic (OCT) imaging system that acquired the world's first 3D-OCT images of the central nervous system of a fruit fly. This technology enabled the realization of a highly miniaturized catheter for early cancer diagnosis in human cavities that were too small to access. He is an international leader and educator in the development of nanotechnology-based multi-modality imaging systems involving X-ray, optical and ultrasound imaging technologies, and has been widely recognized by the scientific community by winning numerous awards, including the Professional Engineers Ontario Excellence Award, Micralyne Microsystems Design Award, the NSERC Innovation Challenge Award, and the Douglas R. Colton Medal for Research Excellence.